Author : Lady G. Lapian*, Arend L. Mapanawang, Welly M. Tuluino, Martha Korompis, Jefry Rompas, Jetje Maidangkay, Said Kudo, Dolfi Buluran, Janbonsel Bobaya
Cholesterol is a lipid, amphipathic and an essential structural component of the membrane and the outer layer of plasma lipoproteins. This compound is synthesized in many tissues from Acetyl CoA (Botham and Mayes, 2009). Golobe Halmahera (Hornstedtia alliacea) is a fruit-producing plant that is a member of the ginger family (Zingiberaciaea). This study aims to determine the effect of Golobe Halmahera (Hornstedtia alliacea) fruit consumption on the decreased levels of total cholesterol in hypercholesterolemia patients in Puskesmas (Public Health Center) Toliwang, West Kao District, North Halmahera Regency in 2016. This research is quasiexperimental design with pretest and posttest control group. With a total sample of 10 respondents, sampling is done by consecutive, non-probability sampling. Results of statistical test (SPSS) shows significant value = 0.000 < 0.05, or the value of t-value (12.073) > t-table ((2.776)). This shows that Golobe Halmahera fruits have an influence on the decrease of the total cholesterol levels. Key words: Hypercholesterolemia, decrease of total cholesterol, Golobe Halmahera (Hornstedtia alliacea).
Dr. Arend L Mapanawang, Sp.PD, FINASIM, PhD