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IDENTIFICATION OF NITRIC OXIDE COMPOUNDS IN LAOR (Polychaeta) METHANOL EXTRACT IN TAGALAYA VILLAGE TOBELO HALMAHERA UTARA VILLAGE

Author : Desy Irene Dutu*, Arend L. Mapanawang, Silvister Wungow

Abstract

Background: Laor (Polychaeta) is a typical biota of Maluku waters. Which appears every year in March or April and Laor is proven to be rich in protein. Nitric Oxide is a chemical compound that is important for the transport of electrical signals in cells, and functions in physiological and pathological processes. Likewise, this compound can cause blood vessel dilation or in medical terms it is called a strong vasodilator so that it can reduce blood pressure. Research Objectives: The purpose of this study was to identify Nitric Oxide (NO) compounds contained in Laor by using maceration methods to extract bioactive compounds present in Laor and gas chromatography-spectrometer (GC-MS) mass as a method to identify Nitric Oxide compound. This type of research: the experimental research conducted at the STIKMAH Laboratory (Makariwo Halmahera College of Health Sciences) Results: The results showed that Laor contained amino acid compounds namely L-Triptophan, L-Arginine, L-Aspartic acid, L-Cystine, L-Gultamic Acid, Glycine, L-Histidine, L-Isoleucine, L- Leucine, L-Lysine, L-Methionine, L-Phenylalanine, LProline, L-Serine, L-Threonine, L-Tyrosine, L-Valine, L-Glutamine, L-Hydroxy Proline and L-Asparagine. Conclusion: From the results of the study it can be concluded that in Laor (polychaeta) Nitric Oxide (NO) compounds are not contained. but the results of the research show that in Laor only contained amino acid compounds especially LArginine which can synthesize Nitric Oxide (NO) compounds from Nitric Oxide Synthase (NOS). Keywords: Laor (Polychaeta) GC-MC Nitric Oxide

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