Author : Michavel Moniharapon, Jantje Wiliem Souhaly, Pieter Kakisina*
Red Fruit (Pandanus conoideus Lam) is one type of plant that contains antioxidant of tocoferol, alfatocoferol, and betacaroten, which supposedly netralizise free radical and heal gastric mucosa damaged in white rat (Rattus novergicus) which induced by a Maluku alcoholic drink called as sopi. This research was perfomed to investigate the effect of red fruit in gastric mucosa of rat which is induced by sopi. Mice with an average weight of 200 grams were given a dose of 2.5 ml/200g BB twice daily for 60 days. Then the Rattus novergicus was given the red fruit at a dose of 0.2 ml/200g BB, 0.4 ml/200g BB, and 0.6 ml/200g BB twice daily for 30 days, respectively. The results of this study indi`cate that the effect of red fruit was found to histology of the mucosal gastric of the mice. Provision of the Pandanus conoideus Lam with an effective dose of 0.6 ml/200g BB of mucosal gastric was repaired. While ulcer gastric of the Rattus novergicus were exposed to the type of sopi. Key words: Red Fruit (Pandanus conoideus Lam), tocoferol, sopi, gastric mucosa.
Dr. Arend L Mapanawang, Sp.PD, FINASIM, PhD