Author : Nora L. Sondakh*, Arend L. Mapanawang, Rendra G. Mansa, Maikel Kiling, Leady D. Lamidja, Jetje Maidangkay, Santje M. Tooy, S. Pangkey Mangare, Charles B. Turangan, Yani Karundeng
Hypertension is a public health problem that is common in developing countries and is the second highest cause of death in Indonesia. High blood pressure is also a major risk factor for coronary heart disease. Golobe (Hornstedtia alliacea) is a plant that grows in tropical areas, including in Halmahera. Halmahera people have been using this plant for energy booster during hunting, treatments for injuries and infections, and herbal medicine for indigestion. The purpose of this study is to determine the effects of Golobe (Hornstedtia alliacea) fruit extracts on the decrease of blood pressure in patients with hypertension. This study is Quasi-Experimental Design Control Group with pretest and posttest control group. Simple random sampling is used to collect a sample of 20 respondents. Data analysis technique used is the paired t-test with significance value of = 0.05. The results of the study by comparing the value of p, t-test and t-table using a two-tailed test produce a p-value of 0.001 (> 0.05) and t-value of 4,583 (> 2,262) for the blood pressure in the experimental group. Meanwhile, the test in the control group results in p-value of 0.380 (>0.05) and t-value of 0.923 (<2.262). Thus, it can be concluded that there is an effect of Golobe fruit to changes in blood pressure, as evidenced by the significant value in the experimental group. Key words: Hypertension, Golobe (Hornstedtia alliacea).
Dr. Arend L Mapanawang, Sp.PD, FINASIM, PhD