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COMPARISON OF PROTHROMBINE TIME MEASUREMENT BETWEEN ACL TOP 350 CTS AND CS-2100i

Author : Connie Frances Kumaat, Astuti Giantini*

Abstract

Background: There are many coagulometer that can be used for prothrombin time (PT) measurement. This study was designed to compare the results of PT measured by ACL TOP 350 CTS that uses RecombiPlasTin 2G reagents and by CS-2100i that uses Dade Innovin reagents. Materials and methods: We use 40 citrate plasma samples with PT that have been measured by CS-2100i and we compare them with ACL TOP 350 CTS. Results: We found good agreement and strong correlation for comparison test. Bland Altman analysis show that 95% of the data is in conformity limits. The result of Spearman correlation test was r = 0.975, p = 0.0001. Conclusion: There were an agreement with strong and significant correlation between PT measurement by means of the CS-2100i and ACL TOP 350 CTS. PT test results of both these coagulometers can be used interchangeably. Key words: PT, coagulation, comparison test, reference value.

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