Author : Ramezan Ali Ataee, Ali Mehrabi-Tavana, Mohammad Hosein Ataee, Mohammad Reza Ataee*
Introduction and aims: the carriage rate concurrency of N. meningitidis serogroups and N. lactamica in oropharynx of volunteers preparing for military service before vaccination are remained unknown. The current study aimed to investigate the frequency of N. meningitidis serogroups and N. lactamica in the oropharynx of young adults. Materials and Methods: A total of 300 oropharyngeal swab samples of the young healthy adults were studied during August 2014 to September 2015. Swabs were plated onto enriched selective media. Gram-negative and xidasepositive diplococci were phenotypically, genetically and biochemically identified. The PCR products were subjected sequencing in order to confirm the accuracy of the results. Results: Among 300 young healthy adults with the mean age of 24 years, identified: 25 N. meningitidis strains (8.3%.) which highest frequency was belonging to serogroup C with 12 cases (4%). in 121 cases (40.3%) the N. lactamica was isolated from oropharynx of the subjects. Analyses of the results indicate that in 154 cases (51.3%), none of the mentioned neisseria had not isolated from the orophrynx. Conclusions: Determination of the healthy carriage rate and screening of N. meningitidis with concomitant colonization of the N. lactamica in oropharynx may be crucial for design of meningococcal disease prevention methods.
Dr. Arend L Mapanawang, Sp.PD, FINASIM, PhD