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EFFECT OF BLOOD DONATION ON FERRITIN LEVELS AND LIPID PROFILE IN SUBJECTS WITH CENTRAL OBESITY

Author : Frans Wantania*, Linda Rotty

Abstract

Introduction. Several studies showed that inflammation is associated with the dyslipidemia. Ferritin is one of the inflammation marker which its level influenced by blood donation. Central Obesity in young adults may have benefit by blood donation because of this mechanism. Aim of this study was to compare the lipid profile between routine blood donation and non-routine blood donation subjects with central obesity. Methods: Fourty-one appearantly health male obese subjects were enrolled in this study. To further investigate this topic, a lipid profile and ferritin level were evaluated in 21 routine blood donation male obese subjects and the other 20 non routine blood donation subjects as control. We use t-test to determine the difference of the mean level of Total Cholesterol, LDL, TG, and HDL. Results. Mean level of Total Cholesterol in routine blood donation is lower than control group (198,2 vs 224,52; p=0,011). The LDL level was lower in routine blood donation than non routine group (130,10 vs 153,76 p=0,013), while Triglycerides level was significantly lower in this group (97,75 vs 137,38, p=0,010). In this study, mean level of HDL (46,75 vs 43,57 p=0,276) and Feritin (228,93 vs 269,4) was not significantly different between routine blood donation subjects as compare to control group. Conclusion. Cholesterol, LDL, and TG level in routine blood donation subjects were significantly lower as compare to non-routine blood donation subjects. Key words: Blood Donation, Ferritin, Lipid Profile, Central Obesity.

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