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THE EFFECT OF ETHANOL EXTRACT OF KEBAR GRASS (Biophytum petersianum KLOTZSCH) TOWARDS IMPROVEMENT OF RAT Rattus norvegicus LUNG EXPOSED TO CIGARETTE SMOKE

Author : Ishak B. Lekatompessy*, Ch. D. Umi Bazsary, A. J. A. Unitly

Abstract

Exposed to cigarette smoke is one of the exogenous free radicals, exposure to cigarette smoke it is also associated with stress oxidative. Compounds are able to reduce the free radical in way binding on the free radical known as antioxidants. Kebar grass (Biophytum petersianum Klotzsch) is one of the plants that contains of antioxidants, vitamins, and flavonoids that supposedly has ability to fix the lung damage exposed to cigarette smoke. The aim of the research is to know the effect of ethanol extract of Kebar grass (Biophytum petersianum Klotzsch) in fixing the rat lung exposed to cigarette smoke. Contains of four treatments and three replicates times. Negative control, positive control, dose 0.0675 and 0.135. The result of the study shows that ethanol extract of Kebar grass able to fix the damage of lung on the ductus alveolaris, sacus alveolaris, and alveoli area that exposed to cigarette smoke. So it can be conclude that ethanol extract of Kebar grass can fix the lung in the form of damage ductus alveolaris, sacus alveolaris and alveoli. Key words: Biophytum petersianum Klotzsch, Antioxidants, Cigarette smoke, Lung, Rat.

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