EDITOR BOARD MEMBERS : VIEW ALL
Dr Bikasih Thapa & Dr Maheswar Prasad (Nepal) - Hideo Wada MD PhD (japan) - Dr a Lavra Castrocatesana (Mexico) - Dr Mrs N.M. Hettiarachechui (Srilanka) - Dr Jorge Aldrete Velasco (Mexico) - Prof Hans Peter Kohler (Switzerland) - Dr Hermanus Suhartono S Sp.OG(K) PhD - Dr Isabel Pinheiro (Portugal) - Dr Suranga (Srilanka) - Jovia Dino Jansen Amsterdam,Holand - Hideo Wada MD PhD University Graduate School of Medicine Departement of Moleculer and Laboratory Medicine Japan - DR Bikash Thapa Internal Medicine Nepal University - DR Maheswar Prasad Internal Medicine Nepal University - Dr a Lavra Castro Castresana Colegio de Medicina interna de Mexico - Dr Suransa Manilgama University of Srilanka Internal Departement Medicine - Dr Mrs N.M. Hettiarachechui University of Medicine Srilanka - Dr Jorge Aldrete Velaso .Colegio de Medicina Interna de Mexico - Prof Hans Peter Kholer M.D FACD Profesor of Medicine University ot Switzerland - Dr Ramezan Ali Atace . Baqiyatallah University of Medical Sciences Departement of Micrology Tehran Iran - Ezekiel Wong Toh Yoon Dr. Gastroenterology of Japan - D Eric Beck,MD Bethesda Hospital Capitol Boelevard St Paul USA - Dr Emine Guderen Sahin Istambul University of Internal Medicine Turky - Dr Selmin Toplan Istambul University - Dr Nicholas New Australia - Dr Kughan Govinden. Tropical Infection of Internal Medicine Malaysia - Dr Godfrey M Rwegerera Princes Marina Hospital Bostwana -
ANTIDIABETIC EFFECT OF INULIN FROM Dioscorea esculenta IN STREPTOZOTOCIN-INDUCED DIABETIC RATS

Author : Anita Soraya Soetoko, Azizah Hikma Safitri, Israhnanto Isradji, Koko Agung Tri Wibowo, Avicennia Nandira, Dikta Zanwar Arifin Rafiq, Salma Savita, Ahmad N Al-Baari, Yoyok Budi, Dina Fatmawati*

Abstract

Aims: Antidiabetic effect of Inulin from Dioscorea esculenta tubers in streptozotocin-induced diabetic rats was investigated. Methods: Antidiabetic effect was assessed based on HbA1C level, creatinine level, urea level, and microbiota composition in fecal. Level of HbA1C was determined using spectrophotometry. Level of creatinine and urea in blood serum was determined using enzymatic assay. The colony number of Bifidobacterium sp and Lactobacillus sp was evaluated using the total plate count method. Result: After 14 days of treatment, there was a significant difference between control and inulin-treated groups in the level of HbA1C, creatinine, and urea. The colony numbers of Bifidobacterium sp and Lactobacillus were higher in inulin-treated groups than those of control group (p<0.05). Conclusion: Inulin from Dioscorea esculenta tuber can be used as antidiabetic agent. Key words: Inulin, Dioscorea esculenta, antidiabetic effect.

[ PDF ]

 

Indexing

;;;;;;;;

 

PENGUNJUNG KAMI DARI BERBAGAI BELAHAN DUNIA

Flag Counter